Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the google-analytics-for-wordpress domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php on line 6114 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 Warning: Cannot modify header information - headers already sent by (output started at /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/functions.php:6114) in /customers/9/e/2/bloodgenetics.com/httpd.www/wp-includes/rest-api/class-wp-rest-server.php on line 1893 {"id":239,"date":"2017-01-30T14:18:08","date_gmt":"2017-01-30T14:18:08","guid":{"rendered":"http:\/\/bloodgenetics.com\/?page_id=239"},"modified":"2023-12-07T14:49:28","modified_gmt":"2023-12-07T14:49:28","slug":"panel-anemias-hemoliticas-hereditarias-debidas-membranopatias-esferocitosis-eliptocitosis-piropoiquilocitosis-ovalocitosis-estomatocitosis-sindrome-gilbert-factor-modificado-codigo","status":"publish","type":"page","link":"https:\/\/bloodgenetics.com\/panel-anemias-hemoliticas-hereditarias-debidas-membranopatias-esferocitosis-eliptocitosis-piropoiquilocitosis-ovalocitosis-estomatocitosis-sindrome-gilbert-factor-modificado-codigo\/","title":{"rendered":"Panel de Anemias hemol\u00edticas hereditarias debidas a membranopat\u00edas (esferocitosis, eliptocitosis, piropoiquilocitosis, ovalocitosis, estomatocitosis) y S\u00edndrome Gilbert como factor modificado (C\u00f3digo 10062)"},"content":{"rendered":"

[vc_row type=”vc_default” bg_type=”bg_color” bg_override=”full” css=”.vc_custom_1495359719922{margin-bottom: -70px !important;padding-top: 30px !important;padding-bottom: 40px !important;}” bg_color_value=”#f7f7f7″][vc_column]

SOLICITAR ESTUDIO<\/span><\/a><\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]Estudios gen\u00e9ticos\u00a0por Paneles NGS
\nPanel de Anemias hemol\u00edticas hereditarias debidas a membranopat\u00edas (esferocitosis, eliptocitosis, piropoiquilocitosis, ovalocitosis, estomatocitosis) y S\u00edndrome Gilbert como factor modificado (C\u00f3digo 10062)<\/strong><\/p>\n

 <\/p>\n

Los defectos de la membrana de los gl\u00f3bulos rojos incluyen la esferocitosis hereditaria y la eliptocitosis hereditaria, tambi\u00e9n llamada ovalocitosis. En estas enfermedades hay un defecto en la membrana superficial de los gl\u00f3bulos rojos que los hace tener una forma de esfera en la esferocitosis hereditaria o una forma el\u00edptica\/ovalada en la eliptocitosis hereditaria. Los gl\u00f3bulos rojos de estos pacientes tienen una vida \u00fatil m\u00e1s corta.<\/p>\n

 <\/p>\n

La esferocitosis hereditaria es la causa m\u00e1s com\u00fan de anemia hemol\u00edtica entre las personas de ascendencia del norte de Europa. Menos del 10% de los pacientes con esferocitosis hereditaria se manifiesta con la variante severa de la piropoiquilocitosis hereditaria, que se caracteriza por anemia hemol\u00edtica severa, dependiente de la transfusi\u00f3n, con inicio en la infancia y que tambi\u00e9n puede manifestarse con ictericia neonatal.<\/p>\n

 <\/p>\n

Las complicaciones que pueden ocurrir debido a la anemia severa incluyen retraso del crecimiento, prominencia mandibular y frontal, esplenomegalia y enfermedad temprana de la ves\u00edcula biliar.<\/p>\n

 <\/p>\n

El S\u00edndrome de Gilbert es la alteraci\u00f3n m\u00e1s conocida del metabolismo de la bilirrubina y se manifiesta con un aumento de la bilirrubina no conjugada. Es debido a una deficiencia de la enzima uridina difosfato glucuronil transferasa (UGT) responsable del proceso de conjugaci\u00f3n. En la literatura se han descrito casos en los que coexisten el S\u00edndrome de Gilbert y la esferocitosis hereditaria, situaci\u00f3n que se acompa\u00f1a de un mayor grado de hiperbilirrubinemia con formaci\u00f3n de c\u00e1lculos biliares. Por lo tanto, el S\u00edndrome de Gilbert es un factor modificador de las anemias hemol\u00edticas hereditarias debidas a membranopat\u00edas.<\/p>\n

 <\/p>\n

Referencias<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

    \n
  • Gallagher PG. Abnormalities of the erythrocyte membrane. Pediatr Clin North Am. 60(6):1349-62, 2013. [PubMed: 24237975]<\/li>\n
  • King MJ, Zanella A. Hereditary red cell membrane disorders and laboratory diagnostic testing. Int J Lab Hematol. 35(3):237-43, 2013. [PubMed: 23480868]<\/li>\n
  • Da Costa L, Galimand J, Fenneteau O, Mohandas N. Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders. Blood Rev. 27(4):167-78, 2013. [PubMed: 23664421]<\/li>\n
  • Tavazzi D, Taher A, Cappellini MD. Red blood cell enzyme disorders: an overview. Pediatr Ann. 37(5):303-10, 2008. [PubMed: 18543541]<\/li>\n
  • Iolascon A, Perrotta S, Stewart GW. Red blood cell membrane defects. Rev Clin Exp Hematol. 7(1):22-56, 2003. [PubMed: 14692233]<\/li>\n<\/ul>\n

    [\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

    [vc_row type=”vc_default” bg_type=”bg_color” bg_override=”full” css=”.vc_custom_1495359719922{margin-bottom: -70px !important;padding-top: 30px !important;padding-bottom: 40px !important;}” bg_color_value=”#f7f7f7″][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]Estudios gen\u00e9ticos\u00a0por Paneles NGS Panel de Anemias hemol\u00edticas hereditarias debidas a membranopat\u00edas (esferocitosis, eliptocitosis, piropoiquilocitosis, ovalocitosis, estomatocitosis) y S\u00edndrome Gilbert como factor modificado (C\u00f3digo 10062)   Los defectos de la membrana de los gl\u00f3bulos rojos incluyen la esferocitosis hereditaria y la eliptocitosis hereditaria, tambi\u00e9n…<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_oct_exclude_from_cache":false,"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-239","page","type-page","status-publish","hentry","description-off"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/pages\/239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/comments?post=239"}],"version-history":[{"count":9,"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/pages\/239\/revisions"}],"predecessor-version":[{"id":1754,"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/pages\/239\/revisions\/1754"}],"wp:attachment":[{"href":"https:\/\/bloodgenetics.com\/wp-json\/wp\/v2\/media?parent=239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}